HIPEC (Hyperthermic Intraperitoneal Chemotherapy)

What is HIPEC?

HIPEC (Hyperthermic Intraperitoneal Chemotherapy) is an advanced cancer treatment performed immediately after cytoreductive surgery. The procedure combines extensive tumor removal surgery with heated chemotherapy circulated throughout the abdominal cavity.

How Does HIPEC Work?

After visible tumor deposits are surgically removed, heated chemotherapy is circulated inside the abdomen. The chemotherapy solution is usually maintained between 41°C and 43°C to improve local drug penetration and increase exposure of microscopic cancer cells to treatment.

Which Cancers May Benefit?

• Appendiceal Cancer
• Pseudomyxoma Peritonei
• Colorectal Cancer with Peritoneal Metastases
• Selected Ovarian Cancers
• Selected Gastric Cancers
• Peritoneal Mesothelioma
• Selected Rare Peritoneal Malignancies

Patient Selection

Not all patients are suitable candidates for HIPEC. Selection depends on:

• Primary cancer type
• Peritoneal Cancer Index (PCI)
• Disease distribution
• General health condition
• Performance status
• Previous treatments
• Cardiac and pulmonary fitness

Potential Advantages

• Direct chemotherapy exposure inside the abdomen
• Combined surgical and oncological treatment approach
• May improve local disease control in selected patients
• Part of a multidisciplinary treatment strategy
• Specialized treatment for peritoneal cancers

Possible Risks

• Bleeding
• Infection
• Bowel leakage
• Delayed bowel function
• Blood clot formation
• Respiratory complications
• Kidney function changes
• Extended hospitalization

Required Medical Documents

• Pathology Report
• CT Scan of Chest, Abdomen and Pelvis
• PET/CT (if available)
• Tumor Marker Results
• Previous Chemotherapy History
• Operative Reports
• Recent Blood Tests